As consideration for the services, MSG has paid and will continue to pay Sunovion an agreed-upon monthly service charge for each of the first two years of the Market Access Services Agreement term and any agreed regulatory and training service charges. After the second year of the Market Access Services Agreement term, the monthly service charges will be determined by the parties. In addition, MSG also agreed to (x) reimburse Sunovion for any pass-through expenses it incurs while providing the services, and (y) establish an escrow fund for use by Sunovion to manage any rebates, chargebacks and similar fees. During our fiscal year ended on March 31, 2021, we incurred expenses of $3.8 million under the Market Access Services Agreement. As of March 31, 2021, our outstanding obligation pursuant to the Market Access Services Agreement was $0.4 million.
Sumitomo Dainippon Pharma Loan Commitment
On August 5, 2020, we obtained a debt commitment letter from Sumitomo Dainippon Pharma, as amended by a letter dated September 29, 2020, and then further amended by a letter dated December 22, 2020 (the “2020 Commitment Letter”), pursuant to which, subject to the terms and conditions set forth therein, Sumitomo Dainippon Pharma committed to enter into a new $200.0 million unsecured, low-interest, five-year term loan facility. The 2020 Commitment Letter expired in March 2021. During our fiscal year ended March 31, 2021, we agreed to reimburse $0.1 million to Sumitomo Dainippon Pharma for certain third-party pass-through expenses that it incurred in connection with the 2020 Commitment Letter.
Agreements with Takeda Pharmaceuticals International AG
We entered the following agreements with Takeda Pharmaceuticals International AG (“Takeda”), a shareholder that owned greater than 5% of our outstanding common shares at times during last two fiscal years ended on March 31, 2021, and its affiliate, which agreements were effective during our fiscal years ended on March 31, 2021 and March 31, 2020:
In April 2016, we entered into a license agreement with Takeda, which was amended on August 30, 2016, November 19, 2019 and December 15, 2020. Pursuant to this license agreement, Takeda granted to us an exclusive, royalty-bearing license under certain patents and other intellectual property controlled by Takeda to develop and commercialize the compound TAK-385, which we refer to as relugolix, and the compound TAK-448, which we refer to as MVT-602, and products containing these compounds, in certain territories for all human diseases and conditions. In connection with this license agreement, we issued Takeda a warrant to purchase an indeterminant number of capital shares to Takeda which expired on April 30, 2017. We issued a total of 2,343,624 common shares to Takeda under the warrant prior to its expiration. During our fiscal year ended on March 31, 2021, we incurred royalty expense to Takeda of $0.3 million, which was payable as of March 31, 2021. No amounts were incurred during our fiscal year ended March 31, 2020.
Manufacture and Supply Agreements
In June 2016, we and one of Takeda’s affiliates, Takeda Pharmaceutical Company Limited (“Takeda Limited”) entered into an agreement for the manufacture and supply of relugolix. Under this agreement, Takeda Limited supplied us with, and we have obtained from Takeda Limited, all of our requirements for relugolix drug substance and drug product that were used under our development plans for all indications. Takeda Limited also assisted us with a technical transfer of the manufacturing process for relugolix to us and our designee and we paid the expenses related to such transfer. During our fiscal years ended on March 31, 2021 and 2020, we incurred expenses of $0.2 million and $1.5 million, respectively, under this agreement.
On May 30, 2018, we entered into a Commercial Manufacturing and Supply Agreement with Takeda pursuant to which Takeda has manufactured and supplied us with relugolix drug substance to support the commercial launch of relugolix. Takeda has also assisted with the transfer of technology and manufacturing know-how to a second contract manufacturing organization of one of our subsidiaries, MSG. We paid the expenses related to such transfers. During our fiscal year ended on March 31, 2020, we incurred expenses of $11.2 million under this agreement. During our fiscal year ended on March 31, 2021, we did not have any expenses under this agreement.
Agreements with Roivant
We entered into a series of agreements with Roivant, our former controlling shareholder, and the ones discussed below were effective during our fiscal year ended on March 31, 2020.